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Semisynthetic antitumor agent of plant origin, obtained by chemical synthesis from natural raw materials - European yew needles (Taxus baccata). White or almost white powder, highly lipophilic and practically insoluble in water. The molecular weight of 861.9.
Semisynthetic antitumor agent of plant origin, obtained by chemical synthesis from natural raw materials - European yew needles (Taxus baccata). White or almost white powder, highly lipophilic and practically insoluble in water. The molecular weight of 861.9.
The medicine is used to treat adult patients with a type of skin cancer called melanoma, which has spread to the skin or lymph nodes and cannot be removed surgically.
Kyprolis (Carfilzomib) is a targeted antitumor drug used in the diagnosis of recurrent multiple myeloma, when the patient has already received 1-2 treatments and they have been ineffective.
chronic myeloid leukemia (CML) in adults in the presence of the T1315I mutation; chronic myeloid leukemia (CML) and acute lymphoblastic leukemia (ALL) in the presence of the Philadelphia chromosome, in adults who are not suitable for any of the other protein tyrosine kinase inhibitors.
chronic myeloid leukemia (CML) in adults in the presence of the T1315I mutation; chronic myeloid leukemia (CML) and acute lymphoblastic leukemia (ALL) in the presence of the Philadelphia chromosome, in adults who are not suitable for any of the other protein tyrosine kinase inhibitors.
Xtandi® is a drug for treating advanced prostate cancer. Kstandi is used for the treatment of metastatic prostate cancer, which is not amenable to surgical or drug therapy aimed at lowering testosterone levels.
Patients with mild to moderate impaired renal function do not require dose adjustment.
Contraindicated in severe renal failure (creatinine clearance less than 20 ml / min).
prescription
Manufacturer AstraZeneca
Zoladex LA is used to treat prostate cancer. It works by decreasing the amount of “testosterone” (hormone) that is produced by your body. Zoladex LA is a long-acting form of Zoladex and is given every 12 weeks.
Trophosphamide (also known under the trade name Ixoten or Iksoten) is a new, experimental cytostatic anti-tumor chemotherapeutic drug with an alkylating type of action.
According to the chemical structure, trophosphamide refers simultaneously to derivatives of oxazaphosphorin, and to diamidophosphates, and to derivatives of bis-β-chloroethylamine.
pharmachologic effect
Pharmacological action - gestagenic, antitumor.
At the cellular level, it inhibits the stimulating effect of testosterone metabolites (androgens) on the development of a number of hormone-dependent tumors in both men and women.
When treating during pregnancy or during its onset (it is recommended to avoid), remember the danger to the fetus. At the time of treatment should stop breastfeeding.
prescription
Manufacturer Bristol-Myers
Indications:
• intravesically:
- for the prevention of relapse of superficial bladder tumors after transurethral resection;
- for the treatment of cancer "in place" of the bladder.
• Transdermal:
- for the treatment of malignant melanoma;
- for non-specific immunomodulating therapy for other malignant neoplasms (lung, mammary gland, acute leukemia, lymphosarcoma, osteosarcoma).
adjuvant therapy of stage III colorectal cancer (C according to Duke) after radical resection of the primary tumor in combination with 5-fluorouracil and calcium folinate;
disseminated colorectal cancer (as monotherapy or combination therapy in combination with 5-fluorouracil / calcium folinate);
ovarian cancer (as a second line of therapy).
Docetax belongs to a group of anticancer drugs called taxoids.
Doketax has been prescribed by your doctor for the treatment of breast cancer, special forms
lung cancer (non-small cell lung cancer), prostate cancer, stomach (stomach) or head and neck cancer
In studies of varu animals, flutamide demonstrates the potency of antiandrogenic effect. That exercise is antiandrogenic and si action through inhibirane on androgen and / or through inhibiran nucleonoto svrzvan on androgen in target tekanite or both.
Cases of carcinoma on the prostate in the prediluted stages of Ca sensoryum androgen and rechirate to the therapist with flutamide were reported. When flutamide is used, it can be combined with surgical or medical castration, and comprehension of the scribe affects both testicular, and androgen overdose.
prescription
Manufacturer CSPC Pharmaceutical
Pregnancy and lactation
The drug is contraindicated in pregnancy and lactation. During therapy with Alexan, as well as within 6 months after the end of therapy, women and men of childbearing age should use reliable methods of contraception.
on prescription
Manufacturer Ebewe (Austria)
Anthumor anthracycline antibiotic isolated from Streptomyces peucetius var. caesius.
It has antimitotic and antiproliferative effects. Three main mechanisms of action of doxorubicin are described: interaction with DNA, inhibition of topoisomerase I, DNA and RNA polymerases, the formation of free radicals and direct effects on cell membranes
Pregnancy and lactation
The drug is contraindicated in pregnancy and lactation. During therapy with Alexan, as well as within 6 months after the end of therapy, women and men of childbearing age should use reliable methods of contraception.
on prescription
Manufacturer Ebewe (Austria)
Anthumor anthracycline antibiotic isolated from Streptomyces peucetius var. caesius.
It has antimitotic and antiproliferative effects. Three main mechanisms of action of doxorubicin are described: interaction with DNA, inhibition of topoisomerase I, DNA and RNA polymerases, the formation of free radicals and direct effects on cell membranes
Pregnancy and lactation
The drug is contraindicated in pregnancy and lactation. During therapy with Alexan, as well as within 6 months after the end of therapy, women and men of childbearing age should use reliable methods of contraception.
on prescription
Manufacturer Ebewe (Austria)
Anthumor anthracycline antibiotic isolated from Streptomyces peucetius var. caesius.
It has antimitotic and antiproliferative effects. Three main mechanisms of action of doxorubicin are described: interaction with DNA, inhibition of topoisomerase I, DNA and RNA polymerases, the formation of free radicals and direct effects on cell membranes
Pregnancy and lactation
The drug is contraindicated in pregnancy and lactation. During therapy with Alexan, as well as within 6 months after the end of therapy, women and men of childbearing age should use reliable methods of contraception.
on prescription
Manufacturer Ebewe (Austria)
Therapy of patients with progressive differentiated thyroid cancer refractory to radioactive iodine.
Therapy of patients with progressive differentiated thyroid cancer refractory to radioactive iodine.
ekapeptil depot contains triptorelin (in the form of triptorelin acetate).
Triptorelin is an analogue of GnRH. Triptorelin is an artificially derived derivative of the natural hormone gonadorelin. Suppresses the production of sex hormones in the body.
Antitumor agent alkylating action, contains platinum. The mechanism of action is associated with the formation of cross-links between adjacent pairs of guanine bases in DNA, which leads to the suppression of the biosynthesis of nucleic acids and cell death.
Bicalutamide is a racemic mixture whose antiandrogenic activity is primarily due to the (R) -enantiomer. The drug does not have other endocrine activity. Bicalutamide binds to androgen receptors and, without activating gene expression, suppresses the stimulating effect of androgens. The result of this is a regression of malignant neoplasms of the prostate gland.
Yondelis is the trade name for the antitumor drug trabektin, which is manufactured by pharmaceutical companies Zeltia and Johnson and Johnson.
Yondelis is the trade name for the antitumor drug trabektin, which is manufactured by pharmaceutical companies Zeltia and Johnson and Johnson.